Guang-Xian Zhang Selected Research

Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)

7/2022	Correction to: Matrine Treatment Blocks NogoA-Induced Neural Inhibitory Signaling Pathway in Ongoing Experimental Autoimmune Encephalomyelitis.
1/2022	CSF-1 maintains pathogenic but not homeostatic myeloid cells in the central nervous system during autoimmune neuroinflammation.
1/2022	Oral D-mannose treatment suppresses experimental autoimmune encephalomyelitis via induction of regulatory T cells.
1/2021	IFN-β Acts on Monocytes to Ameliorate CNS Autoimmunity by Inhibiting Proinflammatory Cross-Talk Between Monocytes and Th Cells.
10/2020	A distinct GM-CSF+ T helper cell subset requires T-bet to adopt a TH1 phenotype and promote neuroinflammation.
1/2020	Dimethyl fumarate suppresses granulocyte macrophage colony-stimulating factor-producing Th1 cells in CNS neuroinflammation.
7/2019	Mdivi-1, a mitochondrial fission inhibitor, modulates T helper cells and suppresses the development of experimental autoimmune encephalomyelitis.
1/2019	Combination Therapy With Fingolimod and Neural Stem Cells Promotes Functional Myelination in vivo Through a Non-immunomodulatory Mechanism.
1/2018	Carnosol Modulates Th17 Cell Differentiation and Microglial Switch in Experimental Autoimmune Encephalomyelitis.
1/2018	Elevated expression of granulocyte-macrophage colony-stimulating factor receptor in multiple sclerosis lesions.

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Guang-Xian Zhang Research Topics

Disease

70	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 07/2022 - 03/2002
42	Multiple Sclerosis 01/2022 - 01/2004
30	Inflammation (Inflammations) 01/2022 - 03/2004
26	Demyelinating Diseases (Demyelinating Disease) 01/2020 - 12/2002
22	Autoimmune Diseases (Autoimmune Disease) 11/2020 - 11/2003
12	Neuroinflammatory Diseases 01/2022 - 12/2012
4	Alzheimer Disease (Alzheimer's Disease) 11/2018 - 12/2012
4	Neoplasms (Cancer) 01/2016 - 11/2008
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2018 - 12/2009
3	Neoplasm Metastasis (Metastasis) 01/2018 - 06/2014
2	Rheumatoid Arthritis 01/2020 - 01/2019
2	Neuromyelitis Optica (Devic's Disease) 10/2017 - 11/2016
2	Gliosis 01/2017 - 02/2014
2	Parkinson Disease (Parkinson's Disease) 01/2017 - 10/2015
2	Encephalomyelitis (Myeloencephalitis) 01/2016 - 01/2015
2	Central Nervous System Diseases (CNS Diseases) 04/2015 - 12/2012
2	Nervous System Diseases (Neurological Disorders) 01/2015 - 12/2008
1	Bites and Stings (Sting) 12/2020
1	Channelopathies 10/2017
1	Memory Disorders (Memory Loss) 01/2017
1	Acute Disease 01/2017
1	Chronic Hepatitis B 12/2016
1	1 X-linked Charcot-Marie-Tooth disease 07/2016
1	Disease Progression 11/2015

Drug/Important Bio-Agent (IBA)

17	CytokinesIBA 01/2020 - 01/2004
12	MatrinesIBA 07/2022 - 01/2011
10	Interleukin-12 (IL 12)IBA 10/2020 - 03/2002
10	Therapeutic UsesIBA 01/2019 - 12/2005
10	Interleukin-23 (Interleukin 23)IBA 06/2011 - 02/2003
9	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2021 - 06/2011
8	AntigensIBA 11/2020 - 12/2007
8	fasudil (AT 877)IBA 11/2018 - 10/2014
8	Peptides (Polypeptides)IBA 01/2018 - 12/2007
8	Interleukin-27 (Interleukin 27)IBA 01/2018 - 05/2005
7	Interleukin-10 (Interleukin 10)IBA 01/2016 - 12/2007
6	AutoantigensIBA 11/2020 - 03/2002
6	Proteins (Proteins, Gene)FDA Link 07/2019 - 12/2012
6	Myelin-Oligodendrocyte GlycoproteinIBA 01/2018 - 03/2004
6	Quinolizidine AlkaloidsIBA 10/2017 - 01/2011
5	rho-Associated KinasesIBA 11/2018 - 10/2014
5	Interleukin-17 (Interleukin 17)IBA 04/2013 - 12/2007
4	Interleukin-9 (Interleukin 9)IBA 01/2020 - 10/2010
3	MicroRNAs (MicroRNA)IBA 01/2018 - 01/2014
3	Interleukin-12 Receptors (Interleukin 12 Receptor)IBA 06/2012 - 02/2003
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2020 - 03/2019
2	Fingolimod Hydrochloride (FTY720)FDA Link 01/2019 - 01/2017
2	ChemokinesIBA 01/2018 - 10/2015
2	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 12/2017 - 11/2015
2	Amyloid (Amyloid Fibrils)IBA 01/2017 - 12/2012
2	Presenilin-1IBA 01/2017 - 12/2012
2	Calcitriol (Calcijex)FDA LinkGeneric 01/2017 - 04/2015
2	Galectin 1 (LGALS1)IBA 01/2016 - 08/2013
2	InterleukinsIBA 12/2015 - 12/2007
2	Indicators and Reagents (Reagents)IBA 02/2015 - 12/2005
2	AntibodiesIBA 09/2013 - 03/2004
1	Mannose (D-Mannose)IBA 01/2022
1	Macrophage Colony-Stimulating FactorIBA 01/2022
1	Transforming Growth Factor beta (TGF-beta)IBA 01/2022
1	Drinking WaterIBA 01/2022
1	Serine Proteinase Inhibitors (Serine Protease Inhibitors)IBA 12/2020
1	Primaquine FDA Link 11/2020
1	InterferonsIBA 10/2020
1	Chloroquine (Aralen)FDA LinkGeneric 06/2020
1	CuprizoneIBA 01/2020
1	Ursolic AcidIBA 01/2020
1	Dimethyl FumarateIBA 01/2020
1	Dynamins (Dynamin)IBA 07/2019
1	GTP Phosphohydrolases (GTPases)IBA 07/2019
1	3- (2,4- dichloro- 5- methoxyphenyl)- 2- sulfanyl- 4(3H)- quinazolinoneIBA 07/2019
1	Retinoic Acid Receptors (Retinoic Acid Receptor)IBA 01/2019
1	Am 580 (Am580)IBA 01/2019
1	carnosolIBA 01/2018
1	GraphiteIBA 01/2018
1	DiterpenesIBA 01/2018
1	Orphan Nuclear ReceptorsIBA 01/2018
1	Myelin-Associated GlycoproteinIBA 12/2017
1	Oligodendrocyte-Myelin GlycoproteinIBA 12/2017
1	Aquaporin 4IBA 10/2017
1	anti-aquaporin 4 autoantibodyIBA 10/2017
1	Complement Membrane Attack Complex (Membrane Attack Complex)IBA 10/2017
1	Calcitriol Receptors (Calcitriol Receptor)IBA 09/2017
1	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 01/2017
1	EnzymesIBA 01/2017
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2017
1	tau Proteins (tau Protein)IBA 01/2017
1	kushenIBA 12/2016
1	Complement Inactivating AgentsIBA 11/2016
1	Complement Factor H (Factor H)IBA 11/2016
1	Gap Junction beta-1 ProteinIBA 07/2016
1	Nerve Growth Factor (NGF)IBA 04/2016
1	Polysaccharides (Glycans)IBA 01/2016
1	Carrier Proteins (Binding Protein)IBA 01/2016
1	baicalinIBA 11/2015
1	Nerve Growth Factors (Neurotrophins)IBA 10/2015

Therapy/Procedure

26	Therapeutics 01/2021 - 09/2007
5	Immunomodulation 01/2020 - 12/2009
2	Chinese Traditional Medicine (Traditional Chinese Medicine) 12/2017 - 12/2016
2	Transplantation 01/2017 - 10/2010
2	Intravenous Administration 08/2015 - 03/2002
1	Traditional Medicine (Folk Remedies) 01/2018